Surge testing in Barnet as new case of South African variant found
Surge testing begins in Barnet after one case of South African variant was discovered as huge queues continue in Wandsworth and Lambeth for Covid swabs
- Residents in Barnet will be asked to take a PCR coronavirus test from tomorrow
- One local said she was ‘worried about spreading it, but I can’t test if I have it’
- More than 70 people in parts of south London have been forced to self-isolate
- Some 44 cases of South African variant were found in Wandsworth and Lambeth
- Department of Health is urging people in those areas to take Covid-19 tests
Surge testing will start in Barnet tomorrow after a single case of the South African variant was discovered.
Thousands of residents in Wandsworth and Lambeth are already queuing up to take coronavirus tests after 44 cases of the South African variant were found.
Earlier today the drive to surge-test everyone in the two London boroughs descended into farce as at least two centres showed no appointments for the next fortnight.
Barnet Council said teams of officials will go door-to-door in areas in the N3 postcode to deliver PCR test kits, and a mobile testing unit will be set up in the car park of Finchley Central Station.
Meanwhile, Wandsworth Council said the testing operation was a ‘mammoth task’ but urged all adults in the area to get tested even if they do not have any symptoms.
Facilities offering asymptomatic polymerase chain reaction (PCR) testing have now been opened at Wandsworth Town Hall, Tooting Leisure Centre and the University of Roehampton, as well as Lambeth Town Hall and Brockwell Park.
Thousands of residents in Wandsworth and Lambeth are queuing up to take coronavirus tests after 44 cases of the South African variant were found
People stand in line for coronavirus surge testing on Clapham Common, south London
People aged 11 and over who live, work or travel through those areas are being urged to take a Covid-19 polymerase chain reaction (PCR) test, on top of twice-weekly rapid testing.
Additional testing has also been set up by NHS Test and Trace in the SE16 area of Southwark, where the Department of Health said a case linked to the cluster in Wandsworth and Lambeth has been identified and is self-isolating.
A statement on Barnet Council’s website said: ‘The South African variant of Covid-19 has been found in Barnet.
‘From Thursday 15 April we will start testing people for this variant in specific postcode areas affected in N3 or those who shop on the local high street.’
A steady stream of people joined the lines at pop-up centres on Clapham Common and in Brockwell Park near Brixton on Wednesday morning after they were warned waiting times could reach up to two hours.
And at least two centres in Wandsworth showed no appointments available for the surge period up to April 23.
Louisa Wells, 34, from Camberwell, said the process of queuing and testing in Brockwell Park had taken her about an hour.
‘I saw they were surge testing in the area, and they wanted everyone to get a test, so I did what I was told,’ she said.
People stand in line for coronavirus surge testing on Clapham Common, south London, today
Queues wound around the parklands on Clapham Common on Wednesday afternoon
A member of staff hands out testing kits for the disease on Clapham Common Wednesday
‘I’m not particularly concerned (about the new variant) but obviously any extension of this is concerning.’
Another woman, who lives and works in Lambeth, said she is taking ‘every possible precaution to protect her family… and colleagues’ following the announcement of more cases of the variant.
Wandsworth Council – which is under the control of the Conservative group – and the Department of Health have not responded to MailOnline for a request to comment.
A temporary testing site at Deal Porter Square, next to Canada Water Library, was opened on Wednesday and residents can also collect and drop off home-testing kits from Canada Water Library Theatre.
Sangeeta Leahy, director of public health at Southwark Council, said: ‘We understand that this could be concerning news, but there is no cause for alarm.
‘We are delivering Covid-19 tests to residents in a defined area so that we identify how far, if at all, the variant has spread.
‘This variant of Covid-19 may be more easily passed between people… it is important that we all continue to follow the current rules on social distancing and meeting with people from outside our household.’
Staff hand out home testing kits for the coronavirus disease on Clapham Common in London
People take part in coronavirus surge testing on Clapham Common, south London
Hundreds of people queued in Clapham Common for surge tests on Wednesday afternoon
Downing Street has insisted the outbreak is being taken ‘very seriously’ and ‘strong measures’ have been put in place to prevent it spreading.
A DHSC spokesperson said: ‘Additional surge testing and sequencing has been successfully rolled out in a number of targeted locations to help us suppress, control and better understand Covid-19 variants in circulation.
‘Surge testing has been well received by the public in those areas, with thousands of tests completed and thousands of genomes sequenced.
‘Further data will be provided in due course.’
The BBC reported that the outbreak appears to have been triggered by an individual who travelled from Africa in February.
According to documents seen by the broadcaster, the country involved was not on the red list for mandatory hotel quarantine at that time, but is now.
Speaking on Good Morning Britain, Professor Anthony Harnden, deputy chairman of the Joint Committee on Vaccination and Immunisation (JCVI), urged people not to ‘go wild’ after restrictions were eased on Monday, warning it could lead to the South African variant becoming more prevalent.
The two centres known to have no appointments are Tooting Leisure Centre and Wandsworth Town Hall.
One Balham resident said: ‘If they wanted everyone to be tested, perhaps they should have thought about increasing capacity.
‘You’ve now got people who want to make sure they don’t spread the variant effectively unable to find out whether they have got it or not.’
Members of the public queue for the COVID-19 testing centre at St John’s Church in Waterloo
Both Tooting Leisure Centre and Wandsworth Town Hall have no appointments now available
It comes a day after residents of the two South London boroughs said they were unable to celebrate the easing of lockdown restrictions after being urged to undergo PCR testing for the South African coronavirus variant.
Just hours after boisterous celebrations across English cities following the partial reopening of pubs and restaurants, hundreds of people queued patiently on Tuesday morning at special surge testing centres in the London boroughs of Lambeth and Wandsworth.
More than 70 people in the two boroughs are being forced to self isolate after contracting the South African with all local residents instructed to get tested.
There were also long queues at Lambeth Town Hall and other sites in neighbouring Wandsworth.
Residents waited patiently at Brockwell Park’s surge testing centre for more than an hour as the long queue snaked its way along a hill overlooking the capital.
Ruth Clarke, 23 told MailOnline: ‘I was drinking outside a local pub on Monday night and was looking forward to going out for a meal tonight. Then I heard about this South African variant and thought I’d better get tested.
More than 70 people in Wandsworth and Lambeth are being forced to self-isolate after reportedly contracting the South African variant that could weaken the vaccine
People stand socially distanced as they queue to enter to take a Covid test at a mobile novel coronavirus testing centre in Brockwell Park in south London
WHY ARE SCIENTISTS SO SCARED OF THE SOUTH AFRICAN VARIANT?
The variant has mutations on its spike protein which scientists fear will make it difficult for the immune system to recognise, even in vaccinated people
Real name: B.1.351
When and where was it discovered?
Scientists first noticed in December 2020 that the variant, named B.1.351, was genetically different in a way that could change how it acts.
It was picked up through random genetic sampling of swabs submitted by people testing positive for the virus, and was first found in Nelson Mandela Bay, around Port Elizabeth.
Using a computer to analyse the genetic code of the virus – which is viewed as a sequence of letters that correspond to thousands of molecules called nucleotides – can help experts to see where the code has changed and how this affects the virus.
What mutations did scientists find?
There are two key mutations on the South African variant that appear to give it an advantage over older versions of the virus – these are called N501Y and E484K.
Both are on the spike protein of the virus, which is a part of its outer shell that it uses to stick to cells inside the body, and which the immune system uses as a target.
They appear to make the virus spread faster and may give it the ability to slip past immune cells that have been made in response to a previous infection or a vaccine.
What does N501Y do?
N501Y changes the spike in a way which makes it better at binding to cells inside the body.
This means the viruses have a higher success rate when trying to enter cells when they get inside the body, meaning that it is more infectious and faster to spread.
This corresponds to a rise in the R rate of the virus, meaning each infected person passes it on to more others.
N501Y is also found in the Kent variant found in England, and the two Brazilian variants of concern – P.1. and P.2.
What does E484K do?
The E484K mutation found on the South African variant is more concerning because it tampers with the way immune cells latch onto the virus and destroy it.
Antibodies – substances made by the immune system – appear to be less able to recognise and attack viruses with the E484K mutation if they were made in response to a version of the virus that didn’t have the mutation.
Antibodies are extremely specific and can be outwitted by a virus that changes radically, even if it is essentially the same virus.
South African academics found that 48 per cent of blood samples from people who had been infected in the past did not show an immune response to the new variant. One researcher said it was ‘clear that we have a problem’.
Vaccine makers, however, have tried to reassure the public that their vaccines will still work well and will only be made slightly less effective by the variant.
How many people in the UK have been infected with the variant?
At least 544 Brits have been infected with this variant, according to Public Health England’s random sampling.
The number may be higher, however, because PHE has only picked up these cases by randomly scanning genetic sequences of cases identified.
They are thought to have covered every case last week.
Will vaccines still work against the variant?
So far, Pfizer and Moderna’s jabs appear only slightly less effective against the South African variant.
Researchers took blood samples from vaccinated patients and exposed them to an engineered virus with the worrying E484K mutation found on the South African variant.
They found there was a noticeable reduction in the production of antibodies, which are virus-fighting proteins made in the blood after vaccination or natural infection.
But it still made enough to hit the threshold required to kill the virus and to prevent serious illness, they believe.
There are still concerns about how effective a single dose of vaccine will be against the strain. So far Pfizer and Moderna’s studies have only looked at how people given two doses react to the South African variant.
Studies into how well Oxford University/AstraZeneca‘s jab will work against the South African strain are still ongoing.
Johnson & Johnson actually trialled its jab in South Africa while the variant was circulating and confirmed that it blocked 57 per cent of coronavirus infections in South Africa, which meets the World Health Organization’s 50 per cent efficacy threshold.
‘It’s taken the shine off the easing of the lockdown and ruined my plans. I was hoping that things were returning to normal but we can’t seem to get rid of coronavirus. It’s like a monkey on our backs.’
Fitness instructor Deleoy Smith, 36 said: ‘Just when we had some good news about shops and restaurants reopening we now get hit with the South African variant. When will this ever stop.
‘Of course it’s made me nervous about going out. I was looking forward to going for a drink tonight with some pals but don’t think I’ll bother until I get my test result.’
Raymond Campbell, 29 who had taken a day off work to get a test said: ‘It feels as if the whole country is celebrating but not us.
‘I was planning to go into the West End of London tonight for a drink after seeing the party atmosphere there on the news. But this South African strain has got me worried again so I won’t bother.’
Officials revealed that a second testing site is to be set up at Brockwell Park on Wednesday to cope with the huge demand.
Scores of people queued outside Lambeth Town Hall where testing capacity is also set to be increased over the coming days.
Irene Sullivan, 67 who had just had a test said: ‘Having the South African strain in our area is terrible news, especially for young people in our area.
It came after everyone in Lambeth and Wandsworth was today urged to book a coronavirus test after a cluster of the troublesome South African variant was spotted in the two London boroughs.
Public Health England revealed last night up to 74 cases of the mutant strain were discovered in the council areas, in what officials called a ‘significant’ outbreak.
The variant, known as B.1.351, is of concern because it is feared it may be able to partially evade existing vaccines.
Dr Ruth Hutt, director of public health for Lambeth Council, insisted officials were ‘fairly confident’ most cases had been found.
But she added there was a risk cases of the variant had already spilled over into the wider community. A cluster of infections was picked up in a care home.
Dr Hutt told BBC Radio 4’s Today programme that residents of the two boroughs can still enjoy the easing of lockdown — but urged them to do so ‘safely’.
‘It is a really good opportunity now to mobilise all this testing just to check we don’t have any further cases of this variant in either Lambeth or Wandsworth,’ she said.
Dr Hutt added that ‘a lot’ of the cases were picked up through asymptomatic testing, saying it was proof that there were ‘really good testing processes in place’.
She said: ‘What we want to do is a wider testing across the public of anybody who doesn’t have symptoms to check there aren’t further cases out there that we may have missed.’
Ministers have been fighting to stop the mutant variant from spreading rapidly.
More than 540 cases have already been spotted in Britain.
Surge testing has been used in dozens of areas where the variant has been detected. Travellers are also asked to quarantine, in an attempt to stop cases being imported.
Surge PCR testing is available for people aged 11 and over who live, work or travel through these boroughs.
PHE revealed yesterday there were 44 confirmed cases of the variant in the areas, and 30 probably cases linked to these individuals.
The chief medical adviser for NHS Test and Trace, Dr Susan Hopkins, said the clusters were ‘significant’.
‘It’s really important people in the local area play their part in stopping any further spread within the local community,’ she added.
‘Around one in three people with Covid don’t show any symptoms.
‘By taking part you can protect yourselves and your loved ones and help us identify any possible new cases that would otherwise be missed, preventing further transmission and saving lives.’
The B.1.351 strain has three key mutations on its spike protein which help it ‘hide’ from the immune system, known as E484K, N501Y and K417N.
Covid uses its spike to latch onto human cells and the current crop of vaccines have been designed to train people’s bodies to recognise that protein.
But any deformities make it harder for the immune system to spot and flush it out, allowing the virus to take hold.
No10’s scientific advisers fear the South African variant — which has yet to take hold in the UK — may make the current crop of vaccines around 30 per cent less effective.
Analysis by SAGE found the strain can cause up to a 10-fold decrease in the effectiveness of antibodies in vaccinated or previously infected people.
While antibodies are not the only part of the immune response against Covid — white blood cells also help — they play a crucial role in fighting off the infection.
Nonetheless, experts are still confident the jab is strong enough to protect the vast majority of people from falling severely ill with the B.1.351 strain.
South Africa — which has been ravaged by the variant — has already suspended the use of AstraZeneca’s vaccine, citing concerns it is not effective enough.
Testing volunteers are pictured at the make-shift swabbing site in Brockwell Park this morning
And real-world data from Israel last week suggested the strain may also evade the protection provided by Pfizer’s vaccine to some extent.
But separate studies have sought to downplay fears, with one suggesting the Pfizer jab offers 100 per cent protection against the Brazilian and South African variants.
Researchers in Israel compared almost 400 people who had tested positive for Covid, 14 days or more after they received one or two doses of the vaccine, against the same number of unvaccinated patients with the disease.
The variant was found to make up about one per cent of all the Covid cases across all the people studied, according to the study by Tel Aviv University and Israel’s largest health provider Clalit.
But among patients who had received two doses of the vaccine, its prevalence rate was eight times higher than those unvaccinated – 5.4 per cent versus 0.7 per cent.
This suggested the jab is less effective against the South African variant, compared with the original Covid and a variant first identified in Britain that has come to comprise nearly all Covid cases in Israel, the researchers said.
‘This means that the South African variant is able, to some extent, to break through the vaccine’s protection,’ said Tel Aviv University Professor Adi Stern.
The Department of Health has said 44 confirmed Covid-19 cases have been found predominantly in Wandsworth and Lambeth (pictured, Lambeth town hall)
The research cautioned, however, that the study only had a small sample size of people infected with the variant because of its rarity in Israel.
They also said the research was not intended to deduce overall jab effectiveness against any variant, since it only looked at people who had already tested positive for Covid.
Some previous studies have indicated that the Pfizer shot was less potent against B.1.351 variant than against other variants of Covid, but still offered robust defence.
It comes as England’s Covid vaccination roll-out was expanded to over-45s today.
But the NHS website for booking appointments crashed just moments after the drive was officially opened up to younger adults.
Users trying to get a jab were told: ‘The NHS site is currently experiencing technical difficulties. We are working to resolve these issues. Thank you for your patience.’
Other users reported being placed in a queue with a holding screen which read: ‘You are in a queue. Lots of people [are] trying to book an appointment.’
Health chiefs have moved on to the next stage of the campaign because No10 hit its April 15 goal of offering everyone in the top nine priority groups their first dose three days ahead of schedule.
Official data show that 36 areas have given a Covid jab to less than 60 per cent of people in the high-risk age groups. London has a large proportion of the worst-performing areas
But shortly after the site crashed, Vaccines Minister Nadhim Zahawi tweeted that the problem had been ‘fixed’.
Moderna’s vaccine is also being dished out in England from today. But only 20 sites will get supplies of the US company’s jab this week, as supply trickles in at around 150,000 a week.
Ministers have bought 17million doses of Moderna’s vaccine, which is the third to be added to the NHS’ ‘armoury’, alongside jabs from Oxford/AstraZeneca and Pfizer.
Moderna’s jab — as well as leftover supplies of AstraZeneca and Pfizer that haven’t been reserved for second doses — will be used to move on to the next phase of the roll-out.
Boris Johnson hailed the ‘hugely significant milestone’ in the race to inoculate the country, as he said the Government would ‘move forward’ on its next goal of inviting every adult for a vaccine by the end of July.
Despite moving on to the next phase of the roll-out, parts of England have still only vaccinated half of citizens over the age of 50.
Some areas of the country have stormed ahead and managed to reach more than 96 per cent of people in their 50s, 60s, 70s, 80s and above, exceeding Number 10’s ambitions.
But others have been sluggish for months, with large sections of their middle-aged and elderly populations still unprotected against Covid.
Official data analysed by MailOnline shows that 36 areas of the country have given a Covid jab to fewer than 60 per cent of people in the high-risk age groups.
London has had the least successful rollout so far and is home to six of the 10 lowest uptake areas.
Source: Read Full Article